Cisplatin and hyponatremia

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August undefined, 2024

WebJan 13, 2024 · In addition, significant hyponatremia signals were detected for oesophageal, lung, and renal cancers. Conclusions: Hyponatremia has been reported in women and patients with lung cancer... WebOnset of severe hyponatremia following cisplatin (CDDP) administration has been previously reported. However, the risk factors associated with hyponatremia still remain unclear. We conducted a retrospective, single-center, case-control study to identify independent risk factors of severe hyponatremia in patients with various types of cancers.

Risk factors for severe hyponatremia related to cisplatin: a ...

WebApr 7, 2024 · Acute overdosage of spironolactone tablets may be manifested by drowsiness, mental confusion, maculopapular or erythematous rash, nausea, vomiting, dizziness, or diarrhea. Rarely, instances of hyponatremia, hyperkalemia, or hepatic coma may occur in patients with severe liver disease, but these are unlikely due to acute overdosage. WebOnset of severe hyponatremia following cisplatin (CDDP) administration has been previously reported. However, the risk factors associated with hyponatremia still remain … slowpitch softball turfs

[Severe Hyponatremia after Cisplatin-Based Chemotherapy : …

WebHyponatremia is one of the common electrolyte disorders associated with cisplatin (CDDP) administration. We report here two cases of hyponatremia associated with CDDP. Case 1 : A 75-year-old man with urothelial carcinoma of bladder (cT3N1M0) underwent neoadjuvant chemotherapy with CDDP and gemcitabi … WebJul 22, 2024 · Cisplatin-induced kidney toxicity is reviewed here. The use of cisplatin in patients with pre-existing kidney dysfunction and the kidney effects of the platinum … WebSep 1, 2002 · (6) The mechanism of cisplatin-induced hyponatremia is thought to be mainly renal salt wasting syndrome (RSWS), (7) (8) (9) (10) (11) (12) (13) and sometimes the syndrome of inappropriate... slow pitch softball t shirts

Syndrome of inappropriate secretion of anti-diuretic hormone …

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Webcisplatin It is a treatment for a number of different types of cancer. How GC works These chemotherapy drugs destroy quickly dividing cells, such as cancer cells. How you have GC You have these drugs into your bloodstream (intravenously). You might have treatment through a long plastic tube that goes into a large vein in your chest. WebJan 1, 2024 · Univariable analysis revealed a high incidence of hyponatremia in patients receiving cisplatin, three-drug combination regimen, two-drug combination regimen with … software to see text messagesWebNov 12, 2024 · Very common (10% or more): Anorexia, hyponatremia Uncommon (0.1% to 1%): Hypomagnesemia Frequency not reported: Dehydration, hypokalemia, … slow pitch softball turf shoes

"WebMar 24, 2024 · Carboplatin and oxaliplatin may have a lower incidence of hyponatremia relative to cisplatin containing regimens. 10 Of course, malignancy-specific risks of … " - Cisplatin and hyponatremia

Cisplatin and hyponatremia

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WebHyponatremia is a common potential complication in cancer patients. It can be related to anticancer medical therapy. Vincristine, vinblastine, cisplatin and cyclophosphamide are the chemotherapeutic agents most frequently associated with hyponatremia. More recently, analogs such as carboplatin and ifosfamide have also been incriminated. WebDec 16, 2024 · Cisplatin (CDDP; cis-dichlorodiammine platinum [II]) is a non-specific drug of the cell cycle with strong cytotoxicity and broad-spectrum antitumor effects; it is widely used in urogenital system tumors, malignant lymphoma, breast cancer, head and neck cancer, non-small cell lung cancer, etc. ( 1 – 3) Cisplatin-induced nephrotoxicity is …

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WebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt wasting … WebJul 8, 2010 · However, less commonly known is that cisplatin can cause hyponatremia. SIADH is commonly blamed for the cause of hyponatremia in the setting of a patient with …

Webmostly solid tumors had hyponatremia, and of these, 11% had moderate (sodium [Na] 120–129 mEq/L) to severe (Na , 120 mEq/L) hyponatremia (1). This is disproportionately higher than the hyponatremia prevalence rates of 15%–30% reported for general medicine admissions (2). In cancer patients with nonsolid tumors, rates of hyponatremia are less. WebMay 19, 2024 · Cisplatin treatment may cause hyponatremia through SIADH, related to both higher secretion of and sensitivity to ADH ( 32 ). Nausea and vomiting, which are …

WebNational Center for Biotechnology Information WebNov 10, 2024 · A phase I clinical trial of cisplatin and dose-escalating crolibulin was conducted in patients with advanced solid cancers, including recurrent or metastatic ATC. Of 16 patients with ATC, there was one patient with a complete response and one with stable disease. ... (33%), hyponatremia (29%), anemia (19%), hypertension during infusion …

WebA 66-year-old woman with small-cell lung cancer was administered chemo-radiotherapy consisting of cisplatin (CDDP) and etoposide (ETP). From day 3, she developed vomiting and hyponatremia that persisted despite fluid infusion and cortico-steroid administration.

WebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including acute kidney injury with reduced glomerular filtration, Fanconi syndrome, and renal tubular acidosis, nephrogenic diabetes insipidus and renal salt wasting syndrome. software to see students pcsWebHyponatremia of grade 3 or above developed in 30.7% of the generic CDDP group compared to 15.1% of the brand-name CDDP group ( P =0.011). Multivariate analysis … slowpitch softball uniform packagesWebNov 21, 2024 · Cisplatin probably causes hyponatremia by causing SIADH and through its effect on the kidneys. ( 5 Trusted Source A Review of Drug-induced Hyponatremia Go to source) Painkillers: Opiates,... slowpitch softball uniform builderWebJun 11, 2024 · INTRODUCTION Hyponatremia represents a relative excess of water in relation to sodium. It can be induced by a marked increase in water intake (primary polydipsia) and/or by impaired water excretion due, for example, to advanced kidney failure or persistent release of antidiuretic hormone (ADH). (See "Causes of hypotonic … slowpitch softball uniformsWebMar 23, 2024 · With a median follow-up of 12 months, 25 patients in the first-line group and 15 patients in the second-line group died of UTUC. For cisplatin-ineligible first-line patients, the median OS was 18.0 months (95% CI 4.1–31.9), the 1-year OS rate was 65.4%, and the median PFS was 5.0 months (95% CI 2.0–8.0; Figure 1A,B). slowpitch softball turf shoesWebcisplatin, docetaxel and 5-fluorouracil-containing chemotherapy who suffered from acute-onset consciousness disturbance due to hyponatremia just after administration of … software to securely wipe hard driveWebJun 2, 2024 · Background: Cisplatin-associated acute kidney injury (C-AKI) is common. Predictive factors of C-AKI include age > 60 years, hypertension, cisplatin dose, diabetes, and serum albumin < 3.5g/L. The association between C-AKI and hypokalemia, hypomagnesemia or hyponatremia has not been well characterized to date. software to see through clothes