Module membership and gene significance

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August undefined, 2024

Web27 aug. 2024 · Mechanically, the potential regulators of blue module were investigated. These findings highlight an important role of the blue module and its affiliated genes in … WebDownload scientific diagram Correlations between gene module memberships and gene significance for the modules associated with clinical traits. from publication: Gene Co-expression Networks Are ...

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Web23 mrt. 2024 · A total of 432 genes were included in the turquoise module . Moreover, we illustrated in turquoise the module membership and gene significance for AF with stroke (correlation coefficient = 0.32, P < 0.001) . In addition, genes in the turquoise module were overlapped with DEGs in GSE66724. Web Module membership and corresponding gene significance and protein-protein interaction (PPI) network construction of two key modules. (A) Module membership in the turquoise module.... trip my france

WGCNA得到模块之后还可以看里面基因的connectivity - 知乎

Web22 apr. 2024 · We therefore selected the pink model for subsequent analysis. We performed an intramodular analysis for the pink module, and the module membership and gene significance showed a very meaningful correlation (and ), indicating that the 160 genes in the pink module tend to be remarkably correlated with NK cells resting infiltration level … Web"Darkred" module membership was highly correlated with gene significance for total cholesterol (r 0.49, p-value 0.001) and gene significance for LDL-C (r 0.63, p-value 1.4 … Web(E) Scatter plot shows the gene module membership and gene significance of the blue module. (F) Common genes with statistical significance in different methods, including survival, one-way ANOVA ... trip murphy car

WGCNA: an R package for weighted correlation network analysis

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Webwhere m was the number of transcript isoforms of gene i as annotated by the Ensemble Database (Version 75). Note that single-transcript genes were excluded from this analysis. Correlations between module members and known cancer-related genes. The expressions of the genes involved in three cancer-related pathways annotated by Kyoto … Web27 feb. 2024 · Fourth, modules were detected using hierarchical clustering and dynamic tree cutting functions. Finally, gene significance (GS) and module membership (MM) correlations were calculated, and the corresponding module gene information was extracted for further analysis. trip murphy herbieWeb10 aug. 2024 · The first chunk is to calculate Gene Significance GS (the absolute value of the correlation between the gene and the trait) and module membership MM (the … trip my plan

"Web16 jun. 2024 · Gene module membership measures how close the expression pattern of a gene is to its eigengene. It is expected that genes with high module membership will have more important functions in the module and are more likely to be related to clinical traits. " - Module membership and gene significance

Module membership and gene significance

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Web18 mei 2024 · a Scatter plot of the correlation of module membership (correlation coefficients between genes with MEgreen module) and gene significance (correlation coefficients between genes with trait of SZ increase). b Heatmap of MEgreen module genes in two B. rapa accessions, which was displayed based on log 2 (FPKM + 1). Web29 dec. 2008 · The WGCNA R software package is a comprehensive collection of R functions for performing various aspects of weighted correlation network analysis. The …

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Web Module membership and corresponding gene significance and protein-protein interaction (PPI) network construction of two key modules. (A) Module membership … Web7 jul. 2024 · Gene significance (GS) was the correlation coefficient between the expression value of a gene and a phenotype, representing the association between genes and …

Web10 mei 2024 · Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed for the genes in modules with clinical interest. Genes with a significance over 0.2 and a module membership over 0.8 were used as hub genes. Web11 nov. 2024 · 1.横坐标：Module Membership in brown module，翻译过来就是：在棕色模块中的模块成员。模块成员是什么鬼？ 2.纵坐标：Gene Significance (GS) for weight， …

Web9 feb. 2024 · Module membership (MM) and gene significance (GS) revealed the correlation between the gene expression and infiltrated immune cell abundance. Genes in modules that were highly associated with infiltrated immune cells (correlation ≥ 0.7 and p value ≤ 0.05) were extracted for further study (GS ≥ 0.5 and MM ≥ 0.5). Web12 aug. 2024 · Just like what have been said, I analyzed the genes in key module by DAVID, with P < 0.05 considered statistically significant. PPI network construction and module selection. According to the standard of gene significance (GS) > 0.3 and module membership (MM) > 0.8, I selected 83 hub genes from the key module.

Web23 jul. 2024 · Module connectivity and is clinical trait relationship identified as the absolute value of the Pearson’s correlation (Module Membership) and gene and the trait (Gene Significance). We set the Module Membership >0.6 and the Gene-Significance >0.3 for candidate hub genes. Moreover, we selected genes in the hub module and applied the …

WebWGCNA gene significance and module membership. I am completing WGCNA on RNAseq data for 3 groups of patients disease responders, non-responders and controls. I am … trip my soulWeb17 mrt. 2024 · When I generate a labeled heatmap (please see the code below) to check the module-trait correlation, I see some modules correlating with some traits. However, … trip myselfWebWe found a module whose eigengene is highly associated with disease status and whose GO results indicate the module genes are associated with inflammatory processes that … trip murphy herbie fully loadedWeb21 okt. 2024 · Correlations between gene module memberships and gene significance for the module “darkred” and Total cholesterol and LDL-C and for the module “purple” and HDL-C. The genes included in the “darkred” module were enriched in canonical IPA disease and function pathways mostly related to inflammatory response and disease … trip my dreamsWeb3 dec. 2024 · B Scatter plots representing the module membership (kME or MM) and gene significance (GS) values of the genes in the co-expressed modules. Genes on the … trip n becca bandWebContent may be subject to copyright. Module and eigengene network plots. A. Barplot of mean gene significance across modules. In this example we use a trait-based gene significance, Equation 2 ... trip n touchWebThis explain why the Module eigengene (1st Principal component) of the turquoise module poorly correlate with the trait 6 (Module-trait relationship table). Perhaps, I … trip name meaning